COVID-19–associated hospitalization rates among all adults declined during January–June 2021 (pre-Delta period), before increasing during July–August 2021 (Delta period).
Data from the CDC COVID-19–Associated Hospitalization Surveillance Network (COVID-NET), a population-based surveillance system for COVID-19–associated hospitalizations, were used to examine trends in severe outcomes in adults aged ≥18 years hospitalized with laboratory-confirmed COVID-19 during periods before (January–June 2021) and during (July–August 2021) Delta variant predominance. As of July 2021, the Delta variant was responsible for nearly all new SARS-CoV-2 infections in the United States.* The Delta variant is more transmissible than previously circulating SARS-CoV-2 variants ( 1) however, whether it causes more severe disease in adults has been uncertain. In mid-June 2021, B.1.671.2 (Delta) became the predominant variant of SARS-CoV-2, the virus that causes COVID-19, circulating in the United States. Havers, MD 1 COVID-NET Surveillance Team ( View author affiliations) View suggested citation Keipp Talbot, MD 21 Jake Ortega, MPH 22 Andrea Price 22 Shikha Garg, MD 1 Fiona P. Billing, MPH 19 Eli Shiltz, MPH 19 Nasreen Abdullah, MD 20 Melissa Sutton, MD 20 William Schaffner, MD 21 H. Bennett, MD 17 Kevin Popham, MPH 18 Laurie M. Ryan, MS 11 Justin Henderson, MPH 12 Val Tellez Nunez, MPH 12 Erica Bye, MPH 13 Ruth Lynfield, MD 13 Mayvilynne Poblete, MA, MPH 14 Chad Smelser, MD 15 Grant R. Openo, DrPH 7 ,8 Kenzie Teno, MPH 10 Andy Weigel 10 Maya L. Alden, MPH 5 Isaac Armistead, MD 5 James Meek, MPH 6 Kimberly Yousey-Hindes, MPH 6 Evan J. Chai, MD 3 ,4 Pam Daily Kirley, MPH 4 Nisha B. Kambhampati, MPH 1 Jennifer Milucky, MSPH 1 Shua J. Taylor, PhD 1 Kadam Patel, MPH 1 ,2 Huong Pham, MPH 1 Michael Whitaker, MPH 1 Onika Anglin, MPH 1 ,2 Anita K.
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